任何一种疾病都可能在某一部分人中易发,也就是说,疾病的发生发展存在着个体差异,乳腺癌也不例外。从临床资料看,有以下情况的妇女属于乳腺癌发病高危人群。有明显家族史者,尤其是一级亲属中(母亲、姐姐)患过乳腺癌的,患病率为正常人群的2～3倍。原因是在她们生殖细胞内抗癌基因发生突变。月经初潮年龄早于13岁或绝经年龄大于55岁者,患病率较之初潮年龄大于17岁或绝经年龄小于45岁者有所增加。 Any kind of disease can be easily transmitted in a certain part of the population. In other words, there are individual differences in the occurrence and development of diseases, and breast cancer is no exception. From the clinical data, women with the following conditions are at high risk of breast cancer. Those with obvious family history, especially first-degree relatives (mother, sister) who have suffered from breast cancer, have a prevalence of 2 to 3 times that of the normal population. The reason is that mutations have occurred in anti-cancer genes in their germ cells. Menarche older than 13 years old or menopause older than 55 years old had an increase in prevalence compared with menarche ages greater than 17 years or menopause ages less than 45 years.