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目的:探讨枫蓼肠胃康颗粒治疗儿童急性肠胃炎所致腹痛的疗效和安全性。方法:将急性肠胃炎所致腹痛的104例患儿作为观察组,所有患儿均应用枫蓼肠胃康颗粒治疗;选取同期治疗的急性胃肠炎所致腹痛患儿54例,给予患儿口服消旋山莨菪碱片,并予以抗感染以及对症支持治疗,对比研究两组患儿的临床疗效和不良反应发生情况。结果:观察组患儿服药后1h有42例疼痛停止,止痛率为40.38%,对照组患儿服药1h后有47例疼痛停止,止痛率为87.04%,两组患儿止痛率差异有统计学意义(P<0.05);观察组6h有效率为85.58%,对照组6h有效率为83.33%,观察组6h有效率高于对照组,但组间差异无统计学意义(P>0.05);观察组12h有效率为90.38%,对照组为83.33%,组间差异有统计学意义(P<0.05);观察组不良反应发生率为2.88%,对照组不良反应发生率为12.96%,差异显著(P<0.05)。两组患儿不良反应没有造成任何不良后果,停药后症状消失。结论:枫蓼肠胃康颗粒在儿童急性肠胃炎所致腹痛的治疗方面具有一定优势,其药效稳定持久,安全性好,值得临床推广应用。
Objective: To investigate the efficacy and safety of Fengliao Changweikang granule in treating children with abdominal pain caused by acute gastroenteritis. Methods: A total of 104 children with abdominal pain caused by acute gastroenteritis were selected as the observation group. All children were treated with Fengliao Changweikang granule. 54 children with abdominal pain caused by acute gastroenteritis were enrolled in this study. Race anisodamine tablets, and anti-infective and symptomatic supportive treatment, comparative study of two groups of children with clinical efficacy and adverse reactions. Results: In the observation group, 42 cases of pain stopped at 1 hour after taking the medicine and the pain-relief rate was 40.38%. In the control group, 47 cases of pain stopped after 1-hour treatment and the pain-relief rate was 87.04%. There was statistical difference between the two groups (P <0.05). The effective rate of observation group 6h was 85.58%, while that of control group 6h was 83.33%. The effective rate of observation group 6h was higher than that of control group, but there was no significant difference between the two groups (P> 0.05) The effective rate of 12h was 90.38% in the control group and 83.33% in the control group, with significant difference between the two groups (P <0.05). The incidence of adverse reactions in the observation group was 2.88% and the incidence of adverse reactions in the control group was 12.96% P <0.05). Adverse reactions in both groups did not cause any adverse consequences, symptoms disappeared after stopping. Conclusion: Fengliao Changweikang granule has some advantages in the treatment of abdominal pain caused by acute gastroenteritis in children. Its efficacy is stable and durable, and its safety is good. It is worthy of clinical application.