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目的探讨三胎妊娠及双胎妊娠的临床特点及母婴妊娠结局。方法回顾性分析于本院终止妊娠的201例双胎妊娠和78例三胎妊娠的临床资料,将三胎妊娠作为研究组,双胎妊娠作为对照组,分析两组间年龄、孕产次、受孕方式及分娩方式、新生儿结局及妊娠期并发症。结果 1研究组促排卵率、产次明显高于对照组,差异有统计学意义(P<0.05);孕次、体外受精-胚胎移值(IVFET)比较差异无统计学意义(P>0.05)。2研究组妊娠期肝内胆汁淤积综合征(ICP)和产后出血的发生率高于对照组,差异有统计学意义(P<0.05)。妊娠期高血压疾病、胎膜早破的发生率差异无统计学意义(P>0.05)。3研究组新生儿平均出生体重明显低于对照组,差异有统计学意义(P<0.05)。研究组新生儿窒息率、新生儿死亡率、胎儿丢失率、34周前早产率及37周前早产率均明显高于对照组,差异有统计学意义(P<0.05)。4研究组平均终止妊娠孕周低于对照组,差异有统计学意义(P<0.05)。两组间剖宫产率及胎儿畸形发生率差异无统计学意义(P>0.05)。结论双胎妊娠及三胎妊娠各有临床特点,三胎妊娠有更差的新生儿妊娠结局,均需要进一步的研究。
Objective To investigate the clinical features of triple pregnancy and twin pregnancy and maternal and infant pregnancy outcomes. Methods The clinical data of 201 cases of twin pregnancy and 78 cases of third trimester pregnancy in our hospital were retrospectively analyzed. The third trimester pregnancy was taken as the research group and the twin pregnancy was taken as the control group. The age, Methods of pregnancy and mode of delivery, neonatal outcomes and complications during pregnancy. Results 1 The rate of ovulation and the number of births in study group were significantly higher than those in control group (P <0.05). There was no significant difference in pregnancy fertility and IVFET (P> 0.05) . The incidence of intrahepatic cholestasis syndrome (ICP) and postpartum hemorrhage in study group 2 was significantly higher than that in control group (P <0.05). The prevalence of hypertensive disorders during pregnancy and premature rupture of membranes was not significantly different (P> 0.05). The average birth weight of neonates in study group was significantly lower than that in control group (P <0.05). Neonatal asphyxia, neonatal mortality, fetal loss, preterm birth 34 weeks before birth and premature birth 37 weeks were significantly higher in the study group than in the control group (P <0.05). The average gestational age at termination of pregnancy in the study group was lower than that in the control group (P <0.05). There was no significant difference in the incidence of cesarean section and fetal malformation between the two groups (P> 0.05). Conclusion Twin pregnancies and three pregnancies have their own clinical features. Third trimester pregnancies have poorer newborns’ pregnancy outcomes, and further studies are needed.