论文部分内容阅读
目的探讨基药内优思灵50R对初发2型糖尿病(T2DM)的治疗效果。方法随机选择2014年1月至2015年12月农合参合初发2型糖尿患者100例,其中50例行优思灵50R治疗为优思灵组,另50例行诺和灵50R治疗为诺和灵组,两组均持续治疗90 d,比较两组治疗后空腹血糖(FPG)、餐后2 h血糖(PG2h)、糖化血红蛋白(Hb A1c)、血清总胆固醇(TC)和血清三酰甘油(TG)、胰岛素用量、体质量变化。结果治疗满90 d两组患者FPG、PG2h、Hb A1c、TC和TG较入院时比较明显改善,差异有统计学意义(P<0.05),但两组治疗后比较,差异未见统计学意义(P>0.05)。两组体质量变化、胰岛素用量比较差异均未见统计学意义(P>0.05)。结论优思灵50R对初发T2DM的治疗效果与诺和灵50R效果相当,适合以餐后血糖升高为主的初发T2DM,可满足卫生院基药内对糖尿病的胰岛素治疗。
Objective To investigate the therapeutic effect of Yousiling 50R in primary drug on type 2 diabetes mellitus (T2DM). Methods A total of 100 patients with newly diagnosed type 2 diabetes mellitus were selected randomly from January 2014 to December 2015. 50 of them were given Yousiling 50R and the other 50 were treated with Norenol 50R And Lingling group. Both groups were treated for 90 days. The levels of fasting blood glucose (FPG), postprandial blood glucose (PG2h), Hb A1c, serum total cholesterol (TC) and serum triglyceride (TG), insulin dosage, body weight change. Results The levels of FPG, PG2h, Hb A1c, TC and TG in the two groups were significantly improved after admission for 90 days (P <0.05), but there was no significant difference between the two groups after treatment P> 0.05). There was no significant difference between two groups in body mass change and insulin dosage (P> 0.05). Conclusion Youshen 50R has the same effect as Norenolone 50R on initial T2DM. It is suitable for the initial T2DM with postprandial hyperglycemia, which can meet the insulin therapy of diabetes in basic medicine of hospitals.