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目的 探讨IgA肾病的临床和病理关系,研究其间可能存在的规律性。方法 根据本组54例IgA肾病患者的临床表现及其病理改变,包括其免疫荧光检查和电镜检查进行综合分析。结果 临床各型IgA肾病的组织病理学都以微小病变为主;但伴有高血压者例外,它以硬化型为主。有大量蛋白尿者,其肾功能损害较重。结论 对临床上不明原因的蛋白尿及血尿患者,必要时可作肾组织活检以资鉴别诊断。
Objective To investigate the clinical and pathological relationship of IgA nephropathy and to study the possible regularity of IgA nephropathy. Methods According to the clinical manifestations and pathological changes of 54 patients with IgA nephropathy in this group, including their immunofluorescence and electron microscopy for a comprehensive analysis. Results The histopathology of all clinical IgA nephropathies was mainly micro-lesions. However, with the exception of hypertension, it was mainly sclerotic. A large number of proteinuria, their renal damage heavier. Conclusion Clinically unexplained proteinuria and hematuria patients, if necessary, can be used for differential diagnosis of renal biopsy.