药物反应性存在种族差异的部分原因是机体对药物的处置存在差异。为阐明药物与血浆成分之间的可逆性相互作用是否为产生这一差异的原因之一,特从健康白种人和华人(各8名)采取血浆标本,对血浆与一些典型药物的结合情况进行研究。受试人员均为不吸烟者,于试验前一周内停服任何药物,禁食一晚后经静脉取血50ml,并制备血浆。药物分别加入血浆制备成临床常见浓度:华法令1μg/ml;安定0.1μg/ml;水杨酸1 Part of the reason for racial differences in drug reactivity is the difference in the way the body treats the drug. To clarify whether reversible interactions between drugs and plasma components are responsible for this discrepancy, plasma samples from healthy Caucasian and Chinese (eight subjects each) were used to determine the association of plasma with some typical drugs research. Subjects were non-smokers, stop taking any drugs within the first week before the test, 50ml intravenous blood after one night of fasted, and prepare plasma. Drugs were added to the plasma to prepare clinical common concentrations: warfarin 1μg / ml; stability of 0.1μg / ml; salicylic acid 1