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目的用三维治疗计划系统评估胸部食管癌传统三野放疗计划的肿瘤剂量分布。方法19例确诊为食管癌的患者均予胸部CT扫描,在CT上勾画GTV,CTV,PTV,然后用CadPlan6.4.7三维治疗计划系统产生传统三野等中心虚拟治疗计划,通过DVH比较GTV,CTV,PTV所受剂量,靶区适形度及靶区剂量均匀度。结果GTV,CTV,PTV最大剂量分别为:51.64,51.94,51.48Gy;最小剂量分别为:41.17,25.31,18.94Gy;平均剂量分别为:49.5,47.34,42.92Gy;适形指数分别为:0.94,0.69,0.38;剂量变异度分别为:2.2,7.57,14.56Gy。结论传统的食管癌设野定位方法不能满足放射治疗的临床剂量学要求,应采用CT定位,通过三维计划系统的方法来确定食管癌的照射方法。
OBJECTIVE: To evaluate the tumor dose distribution of the traditional three-field radiotherapy program for thoracic esophageal cancer using a three-dimensional treatment planning system. Methods Thirteen patients diagnosed as esophageal cancer underwent chest CT scan. GTV, CTV and PTV were sketched on CT. Then, a virtual three-center virtual treatment plan was created by using CadPlan 6.4.7 three-dimensional treatment planning system. GVT, CTV, PTV dose received, target conformality and target dose uniformity. Results The maximum doses of GTV, CTV and PTV were 51.64, 51.94 and 51.48 Gy, respectively. The minimum doses were 41.17, 25.31 and 18.94 Gy respectively. The mean doses were 49.5, 47.34 and 42.92 Gy respectively. The conformal indices were 0.94, 0.69,0.38; dose variation were: 2.2,7.57,14.56Gy. Conclusion The traditional esophageal cancer localization method can not meet the clinical dosimetry requirements of radiation therapy. CT positioning should be adopted and the method of three-dimensional planning system should be used to determine the irradiation method of esophageal cancer.