The dissimilar material resistance spot welding of galvanized high strength steel and aluminum alloy had been conducted. The welded joint exhibited a thin reaction layer composed of Fe2Al5 and Fe4Al13 phases at steel/aluminum interface. The welded joint presented a tensile shear load of 3.3 kN with an aluminum alloy nugget diameter of 5.7 ram. The interfucial failure mode was observed for the tensile shear specimen and fracture occurred at reaction layer and aluminum alloy fusion zone beside the interface. The reaction layer with compounds was the main reason for reduction of the welded joint mechanical property.