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焦炉工因接触含有多环芳烃类混合物的焦炉逸散物而成为患肺癌的高危人群。分子生物学研究结果表明，ｒａｓ癌基因表达产物Ｐ２１蛋白可出现在肺癌的早期阶段，在临床诊断为肺癌前３～２６月（平均１６３月）即发现Ｐ２１阳性，表明Ｐ２１癌蛋白有可能成为肺癌的预报标志...
Coke ovens are at high risk for developing lung cancer due to contact with coke oven fume containing polycyclic aromatic hydrocarbons (PAHs) mixtures. The results of molecular biology showed that P21 protein of ras oncogene can appear in the early stage of lung cancer. P21 was found positive in 3 ~ 26 months before the clinical diagnosis of lung cancer (mean 16.3 months), indicating that P21 oncoprotein may be Become lung cancer forecast sign ...