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目的:探讨妊娠晚期孕妇生殖道B族溶血性链球菌(GBS)带菌情况及临床结局。方法:采用细菌培养法对500例妊娠34~37周孕妇产前阴道下1/3及肛周分泌物进行GBS检测。筛查出GBS阳性孕妇43例(8.60%)作为GBS阳性组;按1∶2配比,选取86例GBS阴性孕妇作为GBS阴性组。随访两组孕妇早产发生率,剖宫产率,产褥感染发生率,胎膜早破、胎儿窘迫及新生儿感染发生率。结果:GBS阳性组孕妇胎膜早破、胎儿窘迫及新生儿感染发生率均高于GBS阴性组;两组早产发生率、产褥感染发生率及剖宫产率比较,差异均无统计学意义(P>0.05)。结论:妊娠晚期孕妇生殖道GBS感染明显增加了胎膜早破、胎儿窘迫及新生儿感染的发生率,应对孕晚期孕妇常规筛查GBS,阳性者积极干预,可改善临床结局。
Objective: To investigate the prevalence and clinical outcome of B-streptococci (GBS) in the third trimester of pregnant women. Methods: The bacterial culture method was used to detect GBS in 500 cases of prenatal vaginal 1/3 and perianal secretions of pregnant women from 34 to 37 weeks of gestation. GBS-positive pregnant women were screened out 43 cases (8.60%) as GBS positive group; According to the ratio of 1: 2, 86 GBS negative pregnant women were selected as GBS negative group. The incidence of preterm birth, cesarean section rate, the incidence of puerperal infection, premature rupture of membranes, fetal distress and neonatal infection were followed up in two groups. Results: The incidences of premature rupture of membranes, fetal distress and neonatal infections in GBS positive group were higher than those in GBS negative group. There was no significant difference in the incidence of preterm birth, puerperal infection and cesarean section between the two groups (P> 0.05). Conclusion: The genital GBS infection of pregnant women during the third trimester significantly increased the incidence of premature rupture of membranes, fetal distress and neonatal infection. It is suggested that GBS should be routinely screened by pregnant women in the third trimester of pregnancy, and positive intervention can improve the clinical outcomes.