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目的：观察人参二醇组皂甙对小鼠体细胞及生殖细胞遗传物质的损伤作用。方法：采用小鼠骨髓嗜多染红细胞MNT及小鼠精子畸形试验。结果：二醇组皂甙不能诱发微核频率和精子畸形频率增高（P＞0．05）。结论：人参二醇组皂甙无诱变活性。
OBJECTIVE: To observe the damage effects of panaxadiol saponins on genetic material of somatic and germ cells in mice. Methods: Mouse bone marrow polychromatic erythrocyte MNT and mouse sperm abnormality test were used. RESULTS: The glycosides of diol group could not induce the frequency of micronucleus and the frequency of sperm abnormalities (P>0.05). Conclusion: Panaxadiol saponins have no mutagenic activity.