论文部分内容阅读
目的:调查了解我国农村居民糖尿病患者痴呆的患病率。方法:选择湖南省慈利县50岁及以上农村居民中的糖尿病患者641例作为观察组,另外选择与其性别、年龄相匹配的非糖尿病患者641例作为对照组。采用入户调查问卷及简易精神状态检查量表(MMSE)进行认知功能的筛查,对MMSE低于划界分者由神经内科医师组成的专家组做进一步检查,并按照美国精神病学会精神障碍诊断与统计手册第4版(DSM-Ⅳ)标准进行痴呆的诊断。结果:(1)观察组完成调查624例,罹患痴呆33例,患病率5.28%(95%CI3.33%～7.82%);对照组完成调查619例,罹患痴呆14例,患病率2.26%(95%CI1.14%～4.01%。观察组痴呆患病率非常显著高于对照组(P<0.01)。(2)观察组50～59岁、60～69岁、70～79岁及80岁以上4个年龄段中痴呆的患病率分别为2.23%(5/224)、4.74%(11/232)、7.33%(8/109)、13.15%(10/76,趋势χ2=16.27,P<0.01);对照组相应年龄段痴呆患病率分别为1.35%(3/222)、1.70%(4/234)、3.57%(4/112)及4.10%(3/73,趋势χ2=8.37,P<0.05)。(3)观察组中男性和女性痴呆患病率分别为3.72%(9/242)和6.01%(24/399),男性和女性痴呆患病率比较,差异显著(P<0.05);对照组中男性和女性痴呆患病率分别为1.68%(5/238)和1.98(8/403),虽然女性痴呆患病率高于男性,但差异不显著(P>0.05)。结论:糖尿病患者痴呆的患病率非常显著高于非糖尿病患者,而且女性糖尿病患者痴呆的患病率显著高于男性糖尿病患者,且两组人群痴呆的患病率均随着年龄增大而升高。
Aims: To investigate the prevalence of dementia in diabetic patients in rural China. Methods: Sixty-one cases of diabetic patients aged 50 years and over in Cili County of Hunan Province were selected as the observation group. Another 641 non-diabetic patients, whose sex and age were matched, were selected as the control group. Screening for cognitive function was conducted using the Household Questionnaire and the Mini-Mental State Examination Scale (MMSE), further examination of a panel of neurologists with MMSE below the delimitation threshold, and follow-up to the American Psychiatric Association’s Mental Disorders Diagnostic and Statistical Manual Version 4 (DSM-IV) criteria for the diagnosis of dementia. Results: (1) The observation group completed the survey of 624 cases, 33 cases of dementia, the prevalence of 5.28% (95% CI3.33% ~ 7.82%); control group completed survey of 619 cases, dementia in 14 cases, the prevalence of 2.26 (95% CI, 1.14% -4.01%). The prevalence of dementia in the observation group was significantly higher than that in the control group (P <0.01). (2) The observation group was 50-59 years old, 60-69 years old, 70-79 years old and The prevalence rates of dementia in four age groups over 80 years old were 2.23% (5/224), 4.74% (11/232), 7.33% (8/109), 13.15% (10/76, trend χ2 = 16.27 , P <0.01). The prevalences of dementia in the corresponding age group were 1.35% (3/222), 1.70% (4/234), 3.57% (4/112) and 4.10% (3/73, trend χ2 = 8.37, P <0.05). (3) The prevalence of dementia in men and women in the observation group was 3.72% (9/242) and 6.01% (24/399) respectively. The prevalence of dementia in men and women was significantly different (P <0.05). The prevalence of dementia in male and female was 1.68% (5/238) and 1.98 (8/403) respectively in the control group. Although the prevalence of dementia in women was higher than that in men, the difference was not significant (P> 0.05) .Conclusion: The prevalence of dementia in diabetic patients is significantly higher than that of non-diabetic patients, and the prevalence of dementia in female diabetic patients is significantly higher than that of male diabetic patients Group prevalence of dementia increases with age population rises.