香菇多糖(Lentinan)最早由日本的Chihara等从香菇中提取。大量研究表明,香菇多糖是具有一定抗肿瘤作用的免疫促进药物,它主要通过加强宿主抗肿瘤的细胞免疫机制,产生抗肿瘤效应。香菇多糖是一种良好的免疫增强剂,在我国已被广泛应用于治疗多种肿瘤[1-2]。为了解香菇多糖对结直肠癌术后化疗患者免疫功能的影响,我科于2008年10月 Lentinan was first extracted from shiitake mushrooms by Japan’s Chihara et al. A large number of studies have shown that lentinan is an immune-promoting drug that has certain anti-tumor effect. It mainly produces anti-tumor effect by strengthening the cellular anti-tumor immune mechanism of the host. Lentinan is a good immune enhancer, has been widely used in our country to treat a variety of tumors [1-2]. To understand the impact of lentinan on the immune function of patients with postoperative chemotherapy of colorectal cancer, our department in October 2008