鲎试剂是从海生动物鲎提取的鲎血细胞溶解物制成的一种冻干试剂。这种试剂可与微量细菌内毒素起凝胶反应,从而用来检测内毒素的一种实验技术,称为鲎试验。近年来国外很多报导普遍认为该法检测内毒素确实是一种快速、简便、灵敏的方法。鲎试验起初应用于诊断病人内毒素血症,随后很快被用于革兰氏阴性细菌脑膜炎,尿路感染等疾病的快速、敏感诊断,以及放射性同位素药品,抗菌素的热原检测,卫生学上也用来检测各种水质和食品污染的程度。引起我们极大兴趣的是 Moaulog 等[1]用鲎试验法对100批输液和放射性药品的热原检查,并用家兔法进行对照,两法符合率达96%;Fumarola 等和Ronnlerger 也进行了对照实验,结果两法完全符合[2];Wachtel 等的报道,认为鲎试验 鲎 Reagents is a freeze-dried reagent made from haematopoietic lysates extracted from marine animals. This reagent can react with trace amounts of bacterial endotoxin gel, which is used to detect endotoxin, an experimental technique, known as the 鲎 test. In recent years, many foreign reports generally believe that the method of detecting endotoxin is indeed a fast, simple and sensitive method.鲎 The test was initially applied to the diagnosis of endotoxemia in patients and was quickly used for the rapid and sensitive diagnosis of diseases such as gram-negative bacterial meningitis and urinary tract infections as well as radiodiagnostic drugs, pyrogen detection of antibiotics, hygiene Also used to detect a variety of water quality and food contamination levels. Of great interest to us was Moaulog et al. [1] examining the pyrogen of 100 batches of transfusions and radiopharmaceuticals using the 鲎 test and comparing them with the rabbit method, with a 96% agreement between the two methods; Fumarola et al. And Ronnlerger Control experiments, the results of the two laws in full compliance with [2]; Wachtel et al reported that 鲎 test