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1998年2月～2001年2月,我院采用纳络酮和脑活素治疗新生儿缺氧缺血性脑病(HIE)80例,取得了满意的疗效。 一般资料:本组160例,均符合HIE诊断及分型诊断标准。治疗组男46例,女34例;日龄30分钟～72小时,体重2.5～3.5kg,Apgar评分:1分钟<3分,5分钟<6分。其中轻度窒息23例,中度40例,重度17例。难产38例,羊水混浊42例。早产6例,宫内窘迫74例。对照组男48例,女32例;日龄30分钟～72小时,体重2.5～4kg,Apgar评分:1分钟<3分,5分钟<6分。其中轻度窒息26例,中度窒息38例,重度窒息16例。难产36例,羊水混浊34例。早产12例,宫内窘迫68例。 治疗及观察方法:两组均予保持呼吸道通畅、吸氧、应用
From February 1998 to February 2001, 80 cases of neonatal hypoxic ischemic encephalopathy (HIE) were treated with naloxone and cerebrolysin in our hospital, and satisfactory results were obtained. General information: This group of 160 cases, are in line with HIE diagnosis and classification of diagnostic criteria. The treatment group of 46 males and 34 females; day age 30 minutes to 72 hours, body weight 2.5 ~ 3.5kg, Apgar score: 1 minute <3 minutes, 5 minutes <6 minutes. Among them mild asphyxia in 23 cases, moderate in 40 cases and severe in 17 cases. 38 cases of dystocia, 42 cases of cloudy amniotic fluid. Premature birth in 6 cases, 74 cases of intrauterine distress. Control group, 48 males and 32 females; day age 30 minutes to 72 hours, body weight 2.5 ~ 4kg, Apgar score: 1 minute <3 minutes, 5 minutes <6 minutes. Among them, mild asphyxia in 26 cases, moderate asphyxia in 38 cases and severe asphyxia in 16 cases. 36 cases of dystocia, 34 cases of cloudy amniotic fluid. Preterm birth in 12 cases, 68 cases of intrauterine distress. Treatment and observation methods: Both groups were to maintain airway patency, oxygen, application