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目的:了解我院药品不良反应(ADR)发生的特点及引发的相关因素,为临床合理用药提供依据,保障临床用药安全。方法:对我院2014年上报的80例ADR报告进行归纳和分析。结果:涉及药品共43种,抗菌药物引起的ADR居首位,共27例,占32.15%,其次为中成药和中枢系统用药,分别占25.00%及22.62%;给药途径以静脉注射为主,占98.75%;临床表现以皮肤及附件反应最为常见,占35.09%。结论:ADR的发生与多种因素有关,各相关单位应积极配合,加强ADR的监测工作,为临床合理用药提供参考,减少ADR。
Objective: To understand the characteristics of adverse drug reaction (ADR) in our hospital and the related factors, so as to provide the basis for clinical rational drug use and to ensure the safety of clinical medication. Methods: 80 cases of ADR reported by our hospital in 2014 were summarized and analyzed. Results: There were altogether 43 kinds of drugs involved, and ADR caused by antimicrobial drugs topped the list with a total of 27 cases (32.15%), followed by proprietary Chinese medicines and the central system, accounting for 25.00% and 22.62% respectively. The administration route was mainly intravenous , Accounting for 98.75%. The most common clinical manifestations were skin and accessory reactions, accounting for 35.09%. Conclusion: The occurrence of ADR is related to many factors. All related units should cooperate actively to strengthen the monitoring of ADR, provide a reference for clinical rational drug use and reduce ADR.