新生儿坏死性小肠结肠炎(Neonatal nec-rotizing enterocolitis,NEC)自1965年由Mizrahi提出作为新生儿期的一种独立的疾病以来,国内外报道的病例日渐增多。本病的早期表现与新生儿肺炎、败血症相似,甚易误诊,直至晚期出现明显的胃肠道症状后才考虑本病。现将1977～1981年经尸检证实的4例报告如下: 临床资料男女各2例。发病日龄:<10天者3例,11～30天者1例。分别在5、6、7、8月份发病。均系足月产儿,无围产期异常者。入院后2小时死亡1例,3～4天2例,7天1例。4例的有关资料见表1。讨论新生儿坏死性小肠结肠炎多在生后2天至3周内发病,以2～10天为最高峰。其临床 Neonatal necrotizing enterocolitis (NEC) has been reported by Mizrahi since 1965 as an independent disease in the newborn period. The early manifestation of this disease and neonatal pneumonia, sepsis similar to easily misdiagnosed, until the late obvious gastrointestinal symptoms before considering the disease. Now from 1977 to 1981 confirmed by autopsy in 4 cases reported as follows: Clinical data of 2 cases of both men and women. Age of onset: <10 days in 3 cases, 11 to 30 days in 1 case. Respectively, in 5, 6, 7, August onset. All were full-term children, no abnormal perinatal. 1 case died 2 hours after admission, 3 cases in 4 days 2 cases, 7 days in 1 case. 4 cases of the relevant information in Table 1. Discussion Neonatal necrotizing enterocolitis and more in 2 to 3 weeks after birth onset, with 2 to 10 days as the peak. Its clinical