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目的:了解早产儿生后血清胆红素的动态变化曲线,为我国早产儿黄疸的干预提供参考。方法:选择2007年1～12月本院出生早产儿100例,按胎龄不同分成3组,连续观察10天血清胆红素的变化。结果:3组间血清胆红素值在出生时差异无显著性。72h内血清胆红素递增速度最快,4～5天达高峰,峰值为(11.06±2.69)mg/dl,随后开始逐渐下降。除外病理因素的早产儿血清胆红素值与出生体重及胎龄密切相关。结论:掌握早产儿生后血清胆红素的变化规律,准确评估,连续监测,适时干预,降低黄疸对早产儿神经系统的损害。
Objective: To understand the dynamic changes of serum bilirubin in premature infants and to provide reference for the intervention of jaundice in premature infants. Methods: 100 cases of preterm newborn born in our hospital from January to December 2007 were divided into 3 groups according to different gestational ages, and the changes of serum bilirubin were observed continuously for 10 days. Results: There was no significant difference in serum bilirubin between the three groups at birth. Within 72 hours, serum bilirubin increased most rapidly and peaked at 4-5 days with a peak value of (11.06 ± 2.69) mg / dl, and then began to decline gradually. Except for pathological factors in preterm children with serum bilirubin value and birth weight and gestational age are closely related. Conclusion: The changes of serum bilirubin in preterm infants were grasped accurately, evaluated continuously and intervened timely to reduce the damage of jaundice to nervous system of premature infants.