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目的:观察用氨茶碱治疗喘息性肺炎的临床不良反应,总结导致不良反应的原因及指导今后用药。方法:以我院收治的1例喘息性肺炎患儿(年龄为4个月)作为研究对象,回顾分析其一般资料与相关临床资料,观察将静滴注射氨茶碱这一方案用于治疗喘息性肺炎时,患者出现中毒症状的临床表现,并总结中毒反应发生的原因及应对策略。结果:患儿静滴注射氨茶碱之后,出现极度烦燥、剧烈哭闹、颜面通红、心率增快,肌张力增高等严重中毒反应,给予异丙嗪等治疗之后,中毒症状缓解,5日后肺炎症状痊愈,健康出院。结论:用静滴注射氨茶碱治疗喘息性肺炎患儿时,药物浓度过高或者静滴速度过快均极有可能诱发中毒反应。针对这一现象,医师严格掌握药物特性及用药原则,并在出现中毒反应时,采用相关药物实施有效的治疗。
Objective: To observe the clinical adverse effects of aminophylline in the treatment of asthmatic pneumonia, summarize the causes of adverse reactions and guide future medication. Methods: One case of asthmatic pneumonia (aged 4 months) admitted to our hospital was investigated. The general information and clinical data were retrospectively analyzed. The intravenous infusion of aminophylline was used to treat asthma In patients with pneumonia, the patient developed clinical manifestations of the symptoms of poisoning and summarized the causes of the toxic reactions and the coping strategies. Results: After intravenous injection of aminophylline in children, there was severe irritability, severe crying, flushed face, rapid heart rate, increased muscle tone and other serious toxic reactions. After treatment with promethazine, the symptoms of poisoning were relieved. After 5 days Pneumonia symptoms healed, healthy discharge. Conclusion: Intravenous aminophylline treatment of asthmatic children with asthma, the drug is too high or intravenous infusion rate are likely to induce toxic reactions. In response to this phenomenon, physicians strictly grasp the characteristics of drugs and medication principles, and in the event of toxic reactions, the use of relevant drugs to implement effective treatment.