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卢德新(砀山县人民医院)报道一家母、子、女人口服乙胺嘧啶引起巨幼红细胞性贫血。每日服50mg,连服8天作疟疾预防服药。半月后发生鼻衄、呕血、全身散在性出血点。血常规显示中度贫血,骨髓象示增生活跃,幼稚红细胞数量增加,诊断为巨幼红细胞性贫血。作者指出,本症系因乙胺嘧啶过量所致。用该药时应当警惕。
Lud new (Dangshan People’s Hospital) reported that a mother, son, woman oral pyrimethamine cause megaloblastic anemia. Daily service 50mg, even serving 8 days for malaria prevention medication. Half a month after epistaxis, hematemesis, systemic scattered bleeding point. Blood showed moderate anemia, bone marrow hyperplasia showed active, increased the number of naive erythrocytes, the diagnosis of megaloblastic anemia. The authors note that the disease due to pyrimethamine overdose. Use this medicine should be wary.