目的比较聚桂醇与无水乙醇两种硬化剂超声介入治疗子宫肌瘤的临床疗效及不良反应。方法选择子宫肌瘤患者60例,分为两组,每组30例,使用聚桂醇作硬化剂为观察组,使用无水乙醇作硬化剂为对照组。比较两组的临床疗效及不良反应。结果观察组与对照组患者临床疗效差异无统计学意义(93.3%vs.96.7%)(P>0.05);观察组发生疼痛3例、下腹坠胀1例,无醉酒反应及发热发生;对照组发生疼痛24例、下腹坠胀18例、醉酒反应8例、发热6例。结论聚桂醇硬化剂介入治疗子宫肌瘤疗效与无水乙醇相似,但不良反应发生率低。 Objective To compare the clinical effects and adverse reactions of ultrasonic treatment of two hardeners, poly (lauryl alcohol) and absolute ethanol, in the treatment of uterine fibroids. Methods Sixty patients with uterine leiomyoma were selected and divided into two groups, 30 in each. The rats in the study group were treated with lauromacyl alcohol as sclerotherapy agent and ethanol as the sclerotherapy agent. The clinical efficacy and adverse reactions of the two groups were compared. Results There was no significant difference between the observation group and the control group (93.3% vs.96.7%) (P> 0.05). There were 3 cases of pain in the observation group and 1 case of bulging in the lower abdomen without any alcoholic reaction and fever. The control group 24 cases of pain, abdominal bulge in 18 cases, drunk reaction in 8 cases, fever in 6 cases. Conclusion Lauryl alcohol sclerotherapy interventional treatment of uterine fibroids and ethanol similar efficacy, but the incidence of adverse reactions is low.