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用复方胆酸钠溶液经 T 管灌注溶解胆色素残余结石已初见成效,但存在着疗程较长,肝内结石疗效较差以及因胆石内胆固醇含量增加而影响溶石效果等问题。近年来国内外有以灌注右旋苧烯溶解胆固醇残余结石的成功报导,但其适应症要求结石的胆固醇含量>70%。作者根据桔皮的挥发油90%以上为右旋苧烯,曾以桔皮蒸馏油及其精制品进行溶解胆石的实验,结果发现桔油对胆囊粘膜具有强烈的刺激作用,不宜应用于临床。考虑到我国的胆石绝大多数为混合结石,单用复方胆酸钠溶液或苧烯溶石效果均不甚理想,为此探索一种有效、无害兼能溶解胆固醇和胆
The use of compound sodium cholate solution for T-tube infusion of dissolved bile pigment residual stones has achieved initial success. However, there are problems such as long course of treatment, poor curative effect of intrahepatic stones, and effect of stone dissolution due to increased cholesterol in gallstones. In recent years, successful reports have been reported on the infusion of dextrocycline to remnants of cholesterol in domestic and international markets. However, the indications for the disease include a cholesterol content of >70%. According to the authors, more than 90% of the essential oil of orange peel was dextrorotene. The experiment of dissolving gallstone with orange peel distillate oil and its refined products showed that orange oil has a strong stimulatory effect on gallbladder mucosa and should not be used in clinical practice. Considering that the vast majority of gallstones in China are mixed stones, the effects of using compound sodium cholate solution alone or terpene stone dissolution are not ideal. Therefore, it is necessary to explore an effective and harmless combination of cholesterol and gallbladder.