论文部分内容阅读
本文对氯化钡的免疫毒性进行了研究。结果表明,小鼠经饮水摄入氯化钡1月后,中(10mg/L)、高(100mg/L)剂量组小鼠肝脏有明显病变,脾、淋巴结、胸腺、骨髓、外周血白细胞无明显异常。经conA刺激后,100mg/L剂量组脾淋巴细胞转化率与对照组比明显降低(P<0.05);LPS刺激后,各组间脾淋巴细胞转化率无显著差别。各组脾细胞抗体分泌量亦无显著差别。最低(0.1mg/L)和最高(100mg/L)剂量组腹腔吞噬细胞功能似乎有激活,但与对照组比,统计检验无显著性差异。
In this paper, the immunotoxicity of cesium chloride was studied. The results showed that mice ingested with barium chloride after drinking water for 1 month, the medium (10mg/L), high (100mg/L) dose group mice had obvious lesions in the liver, spleen, lymph nodes, thymus, bone marrow, peripheral blood leukocytes Obviously abnormal. After conA stimulation, the conversion rate of spleen lymphocytes in the 100 mg/L dose group was significantly lower than that in the control group (P<0.05). After LPS stimulation, there was no significant difference in spleen lymphocyte conversion rate between the groups. There was no significant difference in the amount of antibody secreted from spleen cells in each group. The peritoneal phagocytic function appeared to be activated in the lowest (0.1 mg/L) and the highest (100 mg/L) dose groups, but there was no statistically significant difference from the control group.