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本文报道使用不同浓度中药健脾益气合剂及维生素E分别喂养老龄鼠,测定其血液、肝脏、脑组织、脂质过氧化物(lipid peroxide,LPO)含量并与对照组比较,结果显示:中药组老龄鼠血液、肝脏LPO含量明显低于空白对照组P<0.01、差异有显著性意义;维生素E组与空白对照组比较,P>0.05差异无显著性;脑组织LPO含量各组比较,P>0.05差异无显著性。实验结果提示使用中药健脾益气合剂治疗以气虚为临床特征的老年性黄斑变性(senile macular degenration、SMD),可提高体内自由基清除能力,达到保护细胞的正常生理功能。
This article reports the use of different concentrations of Chinese medicine Jianpi Qi mixture and vitamin E feeding old rats, determination of blood, liver, brain tissue, lipid peroxide (lipid peroxide (LPO) content and compared with the control group, the results show that: Chinese medicine The LPO levels in the blood and liver of aged rats were significantly lower than those in the blank control group (P<0.01). The difference between the vitamin E group and the blank control group was not statistically significant (P>0.05); the LPO content in the brain tissue was compared among the groups. >0.05 difference was not significant. The experimental results suggest that the use of traditional Chinese medicine Jianpi Qi Mixture for the treatment of senile macular degeneration (SMD) with clinical features of qi deficiency can increase the ability of free radical scavenging in vivo and achieve the protection of normal physiological functions of cells.