青霉素G的过敏反应报道较多,尤其是过敏性休克。我院儿科使用苄星青霉素G较多,近年来发现在使用过程中,出现了较多的发热反应。这反应属药物热反应,还是药物的一种毒性表现或杂质引起的反应,值得研究。我们对我院1982～1985年的儿科苄星青霉素G的发热反应进行了统计分析。同时,为了进行验证,我们还作了同样药物的家兔发热反应试验。 Penicillin G allergy reported more, especially anaphylactic shock. Pediatric use of benzathine Penicillin G more in our hospital, found in recent years, the use of more fever. This reaction is a thermal reaction of drugs, or drug toxicity or impurities caused by the reaction, it is worth studying. We conducted a statistical analysis of the fever response of pediatric benzathine penicillin G from 1982 to 1985 in our hospital. At the same time, in order to verify, we also made the same drug rabbit fever reaction test.