目的探讨亚低温对重型颅脑损伤患者治疗的影响。方法将重型颅脑损伤患者170例按随机数字表法分为观察组与对照组,各85例,对照组患者给予常规微创血肿清除术,观察组患者在此基础上加用亚低温治疗,同时进行颅内压监测。比较两组患者的治疗效果。结果观察组患者总有效率明显高于对照组;且治疗后两组患者的NIHSS评分与颅内压均明显下降,差异均有统计学意义(均P<0.05)。结论亚低温联合微创手术治疗重型颅脑损伤能有效发挥脑神经保护作用,从而提高疗效。 Objective To investigate the effect of mild hypothermia on the treatment of patients with severe craniocerebral injury. Methods One hundred and seventy patients with severe craniocerebral injury were divided into observation group and control group according to random number table method, 85 cases in each group. Patients in control group were given conventional minimally invasive hematoma removal. Patients in observation group were treated with mild hypothermia on this basis, Simultaneous intracranial pressure monitoring. The treatment effect of two groups of patients was compared. Results The total effective rate in the observation group was significantly higher than that in the control group. The NIHSS scores and intracranial pressure were significantly decreased in both groups after treatment (all P <0.05). Conclusion Mild hypothermia combined with minimally invasive surgery in the treatment of severe craniocerebral injury can effectively exert cerebral neuroprotective effect and improve the curative effect.