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目的分析和研究乌司他丁治疗急性胰腺炎临床疗效。方法 84例急性胰腺炎患者,将其按奇、偶数字表法随机分为观察组与对照组,每组42例。对照组患者给予常规对症治疗;观察组患者在常规治疗基础上加用乌司他丁治疗,将两组患者治疗效果进行对比。结果观察组治疗总有效率高于对照组(P<0.05);治疗前两组患者血、尿淀粉酶检测值比较差异无统计学意义(P>0.05);治疗7 d后,观察组患者血、尿淀粉酶检测值均明显低于对照组,差异具有统计学意义(P<0.05)。结论将乌司他丁应用于急性胰腺炎患者治疗中,其能够有效缓解患者临床症状与体征,抑制炎性细胞因子分泌,对促进血尿淀粉酶恢复及患者病情转归均具有重要作用。
Objective To analyze and study the clinical efficacy of ulinastatin in the treatment of acute pancreatitis. Methods Eighty-four patients with acute pancreatitis were randomly divided into observation group and control group according to odd and even numbers table method, with 42 cases in each group. Patients in the control group were given conventional symptomatic treatment. Patients in the observation group were treated with ulinastatin on the basis of conventional treatment, and the treatment effect was compared between the two groups. Results The total effective rate in the observation group was higher than that in the control group (P <0.05). There was no significant difference in serum amylase levels between the two groups before treatment (P> 0.05). After 7 days of treatment, , Urine amylase test values were significantly lower than the control group, the difference was statistically significant (P <0.05). Conclusion Ulinastatin can be used in the treatment of patients with acute pancreatitis. It can effectively relieve the clinical symptoms and signs of patients and inhibit the secretion of inflammatory cytokines. It plays an important role in promoting the recovery of hematuria and amylase and the prognosis of patients.