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我院内科从1979年以来应用益气化淤方舒心宁治疗冠心病108例,对心绞痛有效率达92.2％,心电图改善率达64.4％,心功能好转率为87％。我们对舒心宁治疗冠心病的有关药理作用进行了药理研究,同时并进行了观察益气药和活血化淤药的作用。舒心宁由益气药黄芪、党参和活血化淤药川芎、红花、当归等组成,其实验方法和结果如下: (一)对大鼠买验性心肌缺血的保护作用: 大鼠24只,分舒心宁和生理盐水(NS)两组,记录Ⅱ导联心电图,静注垂体后叶素0.75—1U/kg后于30秒钟、1、2、3、4、
In our department of internal medicine, since 1979, Yiqi Huayu Shuxinxin has been used to treat 108 cases of coronary heart disease. The effective rate for angina is 92.2%, the improvement rate of ECG is 64.4%, and the improvement rate of heart function is 87%. We performed pharmacological studies on the pharmacological effects of Shuxining in the treatment of coronary heart disease. At the same time, we also observed the effects of Yiqi and blood stasis drugs. Shuxinning consists of Yiqi medicine, Astragalus membranaceus, Codonopsis pilosula, and Rhizoma Chuanxiong, safflower, and angelica, etc. The experimental methods and results are as follows: (1) The protective effect of Buyiqi medicine on experimental myocardial ischemia in rats: 24 rats , Shuxinning and saline (NS) were recorded in two groups. The II lead electrocardiogram was recorded. After intravenous infusion of vasopressin 0.75-1 U/kg in 30 seconds, 1, 2, 3, 4,