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采用THP联合化疗方案治疗恶性肿瘤79例,用ANM代替THP的联合化疗方案治疗80例作为对照组。THP组和ADM组的有效率分别是70.1%和67.6%,P>0.05,差异无显著性。在毒副作用方面,化疗后出现心电图异常者,THP,组占22.8%,ADM组占37.5%,P<0.05,差异有显著性;THP组无Ⅲ度脱发,ADM组Ⅲ度脱发占26.3%;Ⅲ~Ⅳ度白细胞降低,THP组占45.5%,ADM组占28.8%,P<0.01,差异有非常显著性。通过升白细胞治疗,两组病人均能按时化疗。
Thirty-nine patients with malignant tumors were treated with THP combined with chemotherapy, and 80 patients treated with ANM instead of THP were treated as a control group. The effective rates of THP group and ADM group were 70.1% and 67.6%, respectively, P>0.05, the difference was not significant. In terms of toxic and side effects, patients with electrocardiographic abnormalities after chemotherapy, THP, group accounted for 22.8%, ADM group accounted for 37.5%, P <0.05, the difference was significant; THP group without III degree alopecia, ADM group III degree alopecia 26.3%; III to IV degrees of white blood cells decreased, THP group accounted for 45.5%, ADM group accounted for 28.8%, P <0.01, the difference was very significant. Through leukocyte therapy, both groups of patients were able to chronotherapy on time.