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目的 探讨胃泌素水平、病毒性肠炎与小儿急性肠套叠病因的关系。方法 对 30例小儿急性肠套叠、30例病毒性肠炎治疗前后和 30例正常同龄婴幼儿 ,用放射免疫分析法测定其血清胃泌素和胰高血糖素水平。结果 与正常对照组比较 ,病毒性肠炎治疗前的血清胃泌素值无显著差异 ,治疗后的血清胃泌素值有显著升高 (P <0 .0 5 ) ;而肠套叠患儿治疗前后的血清胃泌素值和对照组比较均有显著差异 (P<0 .0 5 )。病毒性肠炎和肠套叠治疗前后的血清胰高糖素值有显著差异 (P <0 .0 5 )。结论 高胃泌素血症和病毒性肠炎可能是小儿急性肠套叠的发病有关。
Objective To investigate the relationship between gastrin level, viral enteritis and etiology of acute intussusception in children. Methods Serum gastrin and glucagon levels were measured by radioimmunoassay in 30 children with acute intussusception, 30 with viral enteritis and 30 with normal infants. Results Compared with the normal control group, there was no significant difference in the serum gastrin level before treatment of viral enteritis and the serum gastrin level was significantly increased after treatment (P <0.05). The treatment of intussusception in children Before and after serum gastrin value and the control group were significantly different (P <0. 05). Serum glucagon levels were significantly different between viral enteritis and intussusception before and after treatment (P <0.05). Conclusion Hypergastrinmia and viral enteritis may be related to the incidence of acute intussusception in children.