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唾液分泌型免疫球蛋白A(SIgA)是口腔粘膜的主要防御因素。用放射免疫扩散法测定唾液的SIgA含量,检查口腔科门诊医务人员55例,年龄20～60岁。对照组40例。年龄25～40岁,无口腔炎,唾液SIgA水平男女之间无差别,平均含量为320mg/L,以此作为正常值。 口腔科医务人员,年龄29岁以下或工龄小于9年者唾液SIgA水平正常;年龄30～39岁组为180mg/L,40～49岁组为160mg/L,50岁以上为280mg/L。工龄10～14年组唾液SIgA含量为160mg/L,15～19年组为120mg/L,20年以上组为240mg/L。口腔科不同职务者唾液SIgA含量:护士为120mg/L,技士180mg/L,矫形科医师160mg/L,外科医师260mg/L,内科医师280mg/L。 口腔科医务工作者唾液SIgA水平降低,可能和长期接触多种变应原有关。
Salivary secreted immunoglobulin A (SIgA) is the major defensive factor in the oral mucosa. Salivary SIgA content was determined by radioimmunoassay, and 55 medical staff of dental department were investigated, aged from 20 to 60 years old. Control group of 40 cases. Aged 25 to 40 years old, no stomatitis, saliva SIgA levels between men and women no difference, with an average content of 320mg / L, as the normal value. Stomatology medical staff, saliva SIgA levels were normal in patients under 29 years of age or at less than 9 years of service; 180 mg / L for aged 30-39 years, 160 mg / L for 40-49 years and 280 mg / L for those over 50 years of age. The SIgA content of saliva was 160mg / L in 10-14 years of service, 120mg / L in 15-19 years group and 240mg / L in 20-year group. SIgA content of saliva in different positions in dentistry: 120mg / L for nurses, 180mg / L for technicians, 160mg / L for orthopedics, 260mg / L for surgeons and 280mg / L for physicians. Stomatological workers' salivary SIgA levels are reduced and may be related to long-term exposure to multiple allergens.