在麻醉犬体内分别应用海轮碱Ⅱ和汉肌松施行控制性降压,同时采用Swan-Ganz漂浮导管温度稀释法观察降压期间的血流动力学效应。结果表明海轮减Ⅱ和汉肌松均有显著的降压效应,起效较快,作用时间较短,可控性较好,对心血管系统抑制轻微,有希望成为较理想的控制性降压药。 In the anesthetized dogs, hypothalamus Ⅱ and hanonymatsu were respectively administered with controlled hypotension, and the hemodynamic effects during the depressurization were observed by Swan-Ganz floating catheter temperature dilution method. The results showed that both the seabed Ⅱ and hanonyong have significant antihypertensive effect, rapid onset, short acting time, good controllability, little inhibition of the cardiovascular system, there is hope to become an ideal controlled hypotensive medicine.