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目的探讨强化生活方式对早期代谢综合征(MS)患者的干预效果,以降低心血管疾病的发生风险。方法将176例早期MS患者随机分为干预组(n=92)和对照组(n=84)。干预组进行为期3个月的强化生活方式干预,对照组不进行生活方式干预。观察3个月后两组患者体质指数(BMI)、腰围、收缩压(SBP)、舒张压(DBP)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、空腹血糖(FPG)水平的变化。结果与3个月前比较,干预后干预组腰围、BMI、SBP、DBP、TG、TC、FPG水平下降,差异均有统计学意义(P<0.05),而对照组各指标干预前后的差异均无统计学意义(P>0.05);干预前后,两组HDL-C和LDL-C的差异均无统计学意义(P>0.05);干预后,与对照组比较,干预组腰围、BMI、SBP、DBP、TG和TC水平降低,差异均有统计学意义(P<0.05)。结论强化生活方式干预是治疗早期MS的有效措施。
Objective To investigate the intervention effect of intensive life style on patients with early metabolic syndrome (MS) and to reduce the risk of cardiovascular diseases. Methods A total of 176 patients with early stage MS were randomly divided into intervention group (n = 92) and control group (n = 84). Intervention group for a period of 3 months of intensive lifestyle intervention, the control group without lifestyle intervention. Body mass index (BMI), waist circumference, SBP, DBP, TG, TC, HDL-C ), Low density lipoprotein cholesterol (LDL-C), fasting blood glucose (FPG) levels. Results Compared with 3 months before the intervention, the levels of waist circumference, BMI, SBP, DBP, TG, TC and FPG in the intervention group decreased significantly (P <0.05), while those in the control group before and after intervention There was no significant difference in HDL-C and LDL-C between the two groups before and after intervention (P> 0.05). After intervention, the waist circumference, BMI, SBP , DBP, TG and TC levels decreased, the difference was statistically significant (P <0.05). Conclusion Intensive life style intervention is an effective measure to treat early stage MS.