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目的 观察CFP/HCPT方案治疗晚期乳腺癌的近期疗效。方法 24例晚期乳腺癌患者分两组,实验组采用CFP/HCPT方案,对照组采用CMFP方案,比较二者的近期疗效和毒副作用。结果 实验组12例中完全缓解2例,部分缓解8例,有效率83.3％;对照组12例中无完全缓解者,部分缓解4例,有效率33.3％。二者差异有显著性。两组毒性主要为消化道反应和骨髓抑制。毒性无显著差异。结论 HCPT对乳腺癌具有一定疗效。
Objective To observe the short-term efficacy of CFP/HCPT regimen in the treatment of advanced breast cancer. Methods 24 patients with advanced breast cancer were divided into two groups. The experimental group was treated with CFP/HCPT regimen, and the control group was treated with CMFP regimen. The short-term efficacy and toxic side effects were compared. Results In the experimental group, there were 2 cases of complete remission, 8 cases of partial remission, and 83.3% effective rate. In the control group, 12 cases had no complete remission, partial remission was 4 cases, and the effective rate was 33.3%. The difference between the two is significant. The main toxicities in the two groups were gastrointestinal reactions and myelosuppression. No significant difference in toxicity. Conclusion HCPT has a certain effect on breast cancer.