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目的观察针对性治疗原发性肾病综合征并发急性肾功能衰竭的临床疗效及对患者生活质量的影响。方法选取该院自2014年1-12月期间所收治的34例原发性肾病综合征并发急性肾功能衰竭患者,根据患者的具体情况实施针对性的治疗,观察其临床疗效及生活质量水平变化。结果 34例原发性肾病综合征并发急性肾功能衰竭患者,经治疗后显效24例(70.6%),有效8例(23.5%),无效2例(5.9%),总有效率为94.1%。治疗后,34例患者生活质量评分为(95.12±4.31)分高于治疗前的(63.71±2.14)分。结论对原发性肾病综合征并发急性肾功能衰竭患者进行早期诊断和针对性的治疗,能够改善临床症状,提高临床疗效及生活质量,值得临床推广使用。
Objective To observe the clinical effect of targeted therapy on patients with primary nephrotic syndrome complicated with acute renal failure and its impact on the quality of life of patients. Methods From January to December 2014 in our hospital, 34 patients with primary nephrotic syndrome complicated with acute renal failure were enrolled. Patients were treated according to the specific conditions and the clinical efficacy and quality of life were observed . Results In 34 patients with primary nephrotic syndrome complicated with acute renal failure, 24 cases (70.6%) were effective after treatment, 8 cases (23.5%) were effective and 2 cases (5.9%) were ineffective. The total effective rate was 94.1%. After treatment, 34 patients with quality of life score (95.12 ± 4.31) points higher than before treatment (63.71 ± 2.14) points. Conclusion Early diagnosis and targeted treatment of patients with primary nephrotic syndrome complicated with acute renal failure can improve clinical symptoms and improve clinical efficacy and quality of life, which is worthy of clinical promotion.