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近年来急性早幼粒细胞白血病(APL)的分子学发病机制逐渐被阐明,其治疗经历了蒽环类药物为主的联合化疗、全反式维甲酸(ATRA)和亚砷酸(ATO)治疗3个阶段。ATRA的应用使得诱导完全缓解(CR)率从单纯蒽环类为主化疗的50%〔1〕提
In recent years, the molecular pathogenesis of acute promyelocytic leukemia (APL) has been gradually clarified. The treatment has undergone anthracycline-based combination chemotherapy, all-trans retinoic acid (ATRA) and arsenious acid (ATO) 3 stages. The use of ATRA makes the induction of complete remission (CR) rate from anthracycline-based chemotherapy alone 50% 〔1〕 mentioned