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目的:探究中西医结合治疗消化性溃疡合并上消化道出血的疗效及对胃内pH的影响。方法:选取90例消化性溃疡合并上消化道出血的患者作为研究对象,并将其按数字随机分组法分为对照组和观察组,每组45例。给予对照组泮托拉唑联合血凝酶进行治疗,观察组则在此基础上结合中医辨证分型方法联合治疗,比较两组患者的止血时间以及治疗效果,监测比较两组患者胃内pH的变化。结果:观察组的止血时间为(32.18±5.9)h,总有效率为91.11%;对照组的相应值分别为(50.24±8.17)h,71.11%。观察组的止血时间明显短于对照组,总有效率也高于对照组,且差异具有统计学意义(P<0.05);两组患者24 h胃内平均pH、到达胃内pH6.0的时间及胃内pH6.0的维持时间无显著性差异(P>0.05)。结论:中西医结合方法治疗消化性溃疡合并出血可有效缩短患者的止血时间,治疗效果显著,值得临床推广应用。
Objective: To explore the curative effect of integrated traditional Chinese and western medicine on peptic ulcer complicated with upper gastrointestinal bleeding and its influence on gastric pH. Methods: Ninety patients with peptic ulcer complicated by upper gastrointestinal hemorrhage were selected as research objects and divided into control group and observation group by digital randomization method, with 45 cases in each group. The control group was treated with pantoprazole and hemagglutinin, and the observation group was combined with TCM syndrome differentiation method on the basis of this method. The bleeding time and the therapeutic effect were compared between the two groups. The gastric pH Variety. Results: The bleeding time in the observation group was (32.18 ± 5.9) h, the total effective rate was 91.11%. The corresponding values in the control group were (50.24 ± 8.17) h and 71.11%, respectively. The bleeding time in the observation group was significantly shorter than that in the control group, and the total effective rate was also higher than that in the control group (P <0.05). In the two groups, the average intragastric pH value within 24 h and the time to reach the intragastric pH value of 6.0 And gastric pH6.0 no significant difference in the maintenance time (P> 0.05). Conclusion: The combination of TCM and Western medicine treatment of peptic ulcer with bleeding can effectively shorten the bleeding time of patients, the treatment effect is significant, worthy of clinical application.