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目的:了解西宁市围产儿主要出生缺陷及主要缺陷发生顺位、构成比等,为制定干预措施,降低出生缺陷发生率,提高人口素质提供理论依据。方法:对西宁市2007~2008年出生缺陷医院监测单位提供的数据进行统计分析,了解主要出生缺陷的顺位、构成比。结果:西宁市2年间共出生围产儿16 265例,其中出生缺陷儿197例,出生缺陷发生率为121.12/万,西宁市出生缺陷前5位依次是:总唇裂、神经管畸形、多指、马蹄内翻足、先天性脑积水;其中城市前3位:总唇裂、多指、神经管畸形;农村前3位:神经管畸形、总唇裂、先天性脑积水(马蹄内翻足并列第3)。结论:西宁市农村出生缺陷发生率高于城市,男婴出生缺陷率略高于女婴,提高产前诊断技术水平,加强优生优育宣传,制定干预措施,降低出生缺陷率,提高人口素质。
OBJECTIVE: To understand the major birth defects and the main defects in Xining City, the order of rank, the composition ratio, etc., for the development of interventions to reduce the incidence of birth defects and improve the quality of population to provide a theoretical basis. Methods: The data provided by monitoring units of birth defects in Xining from 2007 to 2008 were statistically analyzed to find out the rank and ratio of the major birth defects. Results: A total of 16 265 perinatal infants were born in Xining during the two years, 197 of them were born with birth defects. The incidence of birth defects was 121.12 / million. The top 5 birth defects in Xining City were total cleft lip, neural tube defects, Clubfoot, congenital hydrocephalus; where the city before the three: total cleft lip, multi-fingered, neural tube defects; the top three rural areas: neural tube defects, total cleft lip, congenital hydrocephalus (clubfoot parallel 3rd). Conclusions: The incidence of birth defects in rural areas in Xining is higher than that in urban areas. The birth defect rate in male infants is slightly higher than that in female infants. The prenatal diagnosis technique is improved. The publicity of prenatal and postnatal care is strengthened. Interventions are made to reduce the birth defect rate and improve the population quality.