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人体海马的主要功能有:学习、记忆、空间导航以及调节神经内分泌和自主神经活动,海马体是大脑中兴奋发作阈值很低的部位,很多精神性疾病(比如癫痫)的发作与其关系较大,另外,在阿兹海默病中,海马也是首先受到损伤的区域:表现症状为记忆力衰退以及方向知觉的丧失。CA3区锥体神经元是海马中的重要神经元,数量多,功能完善,探索人体大脑海马CA3区锥体神经元的发育过程及其规律对研究大脑海马锥体神经元的形态发育及其功能的完善具有非常重要的意义。然而,在现阶段有关海马神经元发育的研究对象主要集中于大鼠、猴、兔等动物方面,而在人胎海马CA3区锥体神经元形态发育过程的研究却十分缺乏。
The main functions of the human hippocampus are: learning, memory, spatial navigation and regulation of neuroendocrine and autonomic nervous activity. The hippocampus is a site with a very low threshold of excitatory activity in the brain. Many psychiatric diseases (such as epilepsy) In addition, in Alzheimer’s disease, the hippocampus is also the first area to be damaged: the performance of symptoms is memory loss and loss of direction perception. CA3 pyramidal neurons are important neurons in the hippocampus. They are numerous in number and have perfect functions to explore the developmental process of pyramidal neurons in the hippocampal CA3 region of the human brain and their regularity. To study the morphological development and function of pyramidal neurons in the hippocampus The perfection is of great importance. However, at this stage, the research objects related to the development of hippocampal neurons mainly focus on the animals such as rats, monkeys and rabbits. However, the studies on the morphological development of pyramidal neurons in hippocampal CA3 region of human fetuses are scarce.