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目的测量健康中国成人脑红核体积,研究红核体积与侧别、性别、年龄的关系。方法采集21~60岁年龄段健康中国成人志愿者头部磁共振图像,手工分割红核,测量红核体积,使用SPSS16.0软件完成数据统计学分析。结果同性别的左、右侧红核体积差异均有统计学意义(P<0.05),均为左侧>右侧;同侧别男性、女性红核体积差异有统计学意义(P<0.05),均为男性>女性;男性双侧红核体积与年龄均无线性联系,女性双侧红核体积和年龄均呈线性负相关。结论男性、女性红核体积左侧>右侧;同一侧红核体积男性>女性;在21~60岁年龄段男性双侧红核体积随年龄增长均无明显变化,女性随着年龄增长双侧红核体积均有缩小的趋势。
Objective To measure the volume of red nucleus in healthy Chinese adults and to study the relation between the volume of red nucleus and the side, sex and age. Methods Magnetic resonance images of healthy volunteers from 21 to 60 years of age were collected. The red nucleus was manually segmented. The volume of red nucleus was measured. The data were analyzed by SPSS16.0 software. Results There were significant differences in the volume of red nucleus in the same sex between the two groups (P <0.05) , Both were male> female. There was no linear relationship between the volume of bilateral nucleus and age in males. The volume and age of bilateral nucleus in both females were negatively correlated. Conclusions Male and female red nucleus volume left> right side; same side red nucleus volume male> female; There was no significant change of the bilateral nucleus accumbens with age in the 21-60 age group, Red nucleus volume has been reduced.