手足口病是由多种肠道病毒引起的常见传染病,以婴幼儿发病为主。大部分患者症状轻微,以发热和手、足、口腔等部位的皮疹或疱疹为主要特征。少数患者可并发脑膜炎、脑炎、急性迟缓性麻痹、呼吸道感染、心肌炎,个别重症患儿可发生死亡〔1〕。重症病例主要是肠道病毒71型(EV71)感染,也有报道感染柯萨奇病毒A组16型等引起的死亡。近年来, Hand, foot and mouth disease is caused by a variety of enterovirus common infectious diseases, mainly in infants and young children. Most patients with mild symptoms, with fever and hand, foot, mouth and other parts of the rash or herpes as the main feature. A small number of patients may be complicated by meningitis, encephalitis, acute delayed paralysis, respiratory tract infections, myocarditis, some critically ill children can occur [1]. Severe cases are mainly Enterovirus 71 (EV71) infection, there are also reports of Coxsackie virus infection in group A and other 16 caused death. In recent years,