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1 慢性缺氧学说的提出慢性缺氧学说是Fine等在 1 998年提出的〔1〕,在肾病界产生了很大的影响。众所周知 ,在 80年代初Brenner等提出用肾小球血流动力学改变解释肾脏疾病的进行性发展〔2〕,由于这个理论是基于对大鼠试验得出的结论 ,在其他动物身上并没有得到验证
1 Chronic hypoxia theory Chronic hypoxia theory is proposed by Fine et al [1] in 1998, has a great impact in the nephrology. It is well known that in the early 1980s Brenner et al. Proposed explaining the progressive development of renal disease by using glomerular hemodynamic changes [2]. Since this theory is based on the conclusion of the rat experiment, it has not been obtained in other animals verification