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目的了解滨州市沾化区健康体检人群幽门螺杆菌(Hp)感染状况,为该区制定有效的防治Hp感染措施提供依据。方法 2013年1月至2015年1月,对滨州市沾化区1 740名健康查体者进行Hp-IgG抗体测定、快速尿素酶试验(RUT)和14C尿素呼气试验(14C-UBT)。结果1 740人健康体检者中,989例感染Hp,感染率为56.84%(989/1 740)。男性Hp感染率(64.64%)高于女性(45.30%)(P<0.01),青中年Hp感染率(63.12%)高于老年(47.41%)(P<0.01),夫妻组Hp感染率(74.24%)高于非夫妻组(53.73%)(P<0.01),农村组Hp感染率(68.10%)高于城镇组(47.49%)(P<0.01)。结论滨州市沾化区Hp感染率较高,男性与青中年易于感染Hp,Hp感染具有家庭聚集性,与生存环境有关,对于Hp感染应加强预防和及早治疗。
Objective To understand the status of Helicobacter pylori (Hp) infection in healthy medical population in Zhanhua District of Binzhou City, and to provide evidence for the effective prevention and treatment of Hp infection in this area. Methods From January 2013 to January 2015, Hp-IgG antibody, rapid urease test (RUT) and 14C urea breath test (14C-UBT) were performed on 1 740 healthy people in Zhanhua District of Binzhou City. Results Of 1 740 healthy subjects, 989 were infected with Hp, the infection rate was 56.84% (989/1 740). The infection rate of Hp in male was higher than that in female (P <0.01). The infection rate of Hp in male was higher than that of female (45.64%) (P <0.01) 74.24%) were higher than those in non-husband and wife group (53.73%) (P <0.01). Hp infection rate in rural group was 68.10% higher than that in urban group (47.49%) (P <0.01). Conclusions Hp infection rate is higher in Zhanhua District of Binzhou City. Hp is easily infected in both men and adolescences. Hp infection is familial aggregation and is related to living environment. Prevention and early treatment of Hp infection should be strengthened.