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目的报告2例原发软组织骨肉瘤发病及治疗方法,并对其发病特点及治疗情况作初步总结。方法2005年12月及2007年6月,分别收治2例原发软组织骨肉瘤女性患者,年龄44岁和65岁。均因发现包块生长迅速入院。肿瘤分别位于左大腿外侧和左肘关节。病程分别为2个月和6个月。行广泛切除术后常规行放化疗。结果术后病理诊断为软组织骨肉瘤,1例获随访16个月未见复发;另1例于术后10个月因软组织骨肉瘤复发伴肺转移死亡。结论原发软组织骨肉瘤恶性度较高,对于化疗不敏感;保肢手术配合辅助性放疗是其治疗的发展方向。
Objective To report the incidence and treatment of 2 cases of primary osteosarcoma and to summarize its characteristics and treatment. Methods Two female patients with primary soft tissue osteosarcoma, 44 years old and 65 years old, were treated in December 2005 and June 2007 respectively. Due to the rapid growth of mass found in hospital admission. Tumors were located in the left thigh and left elbow joints. Duration of 2 months and 6 months respectively. Routine resection of the line after conventional radiotherapy and chemotherapy. Results Postoperative pathological diagnosis of soft tissue osteosarcoma, 1 case was followed up for 16 months without recurrence; the other 1 case of 10 months after the recurrence of soft tissue osteosarcoma with lung metastasis. Conclusion The primary soft tissue osteosarcoma is highly malignant and is not sensitive to chemotherapy. The limb salvage surgery combined with adjuvant radiotherapy is the development direction of its treatment.