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目的分析冠状动脉支架术后血栓形成的原因,以指导临床治疗。方法回顾性分析近2年我科发生的2例支架内血栓形成患者的临床资料,分析支架后血栓发生原因及处理措施。结果 2例患者均为急性心肌梗死经皮冠状动脉介入术(PCI)治疗后亚急性血栓形成,均存在高龄、弥漫多支病变、合并阿司匹林或氯吡格雷抵抗等因素。结论 PCI术后支架内血栓形成通常是多种因素共同作用的结果,对血栓高危患者应警惕抗血小板药物抵抗的可能性。
Objective To analyze the causes of thrombosis after coronary stent implantation to guide the clinical treatment. Methods Retrospective analysis of 2 cases of stent thrombosis occurred in our department in recent 2 years, the cause of thrombosis and treatment measures were analyzed. Results Both of the two patients were subacute thrombosis after percutaneous coronary intervention (PCI) for acute myocardial infarction. All of them had the characteristics of advanced age, diffuse multifocal disease, with aspirin or clopidogrel resistance. Conclusions Stent thrombosis after PCI is often the result of a combination of multiple factors. Patients with high risk of thrombosis should be alert to the possibility of antiplatelet drug resistance.