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目的分析湖北省食品及公共场所从业人员丙氨酸氨基转移酶(ALT)、甲型肝炎病毒(HAV)和戊型肝炎病毒(HEV)检测结果,为疾病预防控制提供依据。方法以2012~2014年在湖北省黄石市疾病预防控制中心体检的食品及公共场所从业人员56 462例为研究对象,抽取其空腹静脉血进行血清ALT、抗HAV-免疫球蛋白M(Ig M)和抗HEV-Ig M检测,并对检测结果进行统计分析。结果 56 462例体检者中,ALT异常3 622例,异常率为6.415%,其中男2 578例(11.655%),女性1 044例(3.040%),不同性别ALT异常率比较,差异有统计学意义(χ2=1 663.34,P<0.01)。抗HEV-Ig M总阳性率[0.062%(35/56 462)]明显高于抗HAV-Ig M[0.012%(7/56 462)],差异有统计学意义(χ2=18.674,P<0.01);男性抗HAV-Ig M阳性率[0.027%(6/22 119)]高于女性[0.003%(1/34 343)],差异有统计学意义(χ2=6.364,P<0.05)。结论应重视对黄石市食品和公共场所从业人员的定期健康体检,并加大健康教育力度。
Objective To analyze the detection results of alanine aminotransferase (ALT), hepatitis A virus (HAV) and hepatitis E virus (HEV) in food and public places in Hubei Province and provide basis for disease prevention and control. Methods Fifty-six (46 462) employees in food and public places inspected at the Center for Disease Control and Prevention in Huangshi City, Hubei Province during 2012-2014 were enrolled in this study. Serum ALT, anti-HAV- Ig M, And anti-HEV-Ig M test, and the test results were statistically analyzed. Results Among 56 462 cases, there were 3 622 ALT abnormalities with an abnormality rate of 6.415%, of which 2 578 (11.655%) were male and 1 044 (3.040%) were female. There was statistically significant difference in ALT abnormalities Significance (χ2 = 1 663.34, P <0.01). The positive rate of anti-HEV-Ig M was significantly higher than that of anti-HAV-Ig M [0.012% (7/56 462)], with a significant difference (χ2 = 18.674, P <0.01 ). The positive rate of anti-HAV-Ig M in male was 0.027% (6/22 119) higher than that in female [0.003% (1/34 343)], the difference was statistically significant (χ2 = 6.364, P <0.05). Conclusion We should attach importance to regular physical examination of employees of food and public places in Huangshi City and increase health education.