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目的:观察单味丹参及复方丹参液的体外抑瘤作用,明确其是否存在直接细胞毒作用,并比较两者的抑瘤活性.方法:以 M T T 法检测各种不同浓度丹参及复方丹参对 K562 及 B CA P－ 37细胞的体外抑瘤率,并推测其 I C50 值.结果:10μL/M L的丹参、50μL/M L的复方丹参液对 K562 及 B CA P－ 37 细胞的体外抑瘤率均可达 70％ ~80％ ;而对 K562 细胞的 I C50 为丹参 7.51μL/M L、复方丹参 31.0μL/M L;对 B CA P－ 37 细胞的 I C50 分别为丹参6.96μL/M L、复方丹参 34.78μL/M L.结论:单味丹参及复方丹参注射液均存在直接的细胞毒作用,而单味丹参的抗肿瘤作用又强于复方丹参注射液.“,”Objective:To observe the antineoplastic effects of Danshen (red sage root) and Danshen injection in vitro to reveal if the medicine had the cytotoxic effect.Comparsion was made between the two remedies.Methods:The concentrations of Danshen and Danshen injection were used to detect the antineoplastic effects on K562 and BCaP-37 cells in vitro by using MTT Method.IC50 was also measured.Results:10ul/ml Danshen and 50 ul/ml Danshen injection had sig...