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目的:观察欣普贝生在产科促宫颈成熟中的作用。方法:选择2009年10月~2010年9月在吉林大学第二医院产科住院的孕周超过38周、Bishop宫颈评分6分、无妊娠合并症、单胎头位、要求阴道试产的初产妇100例,随机分为两组:观察组50例给予后穹窿放置欣普贝生促宫颈成熟,待宫颈口开大至3 cm,或出现宫缩过强、胎儿宫内窘迫时取出;对照组50例给予催产素促宫颈成熟。观察两组的总产程、阴道出血量、新生儿窒息率、剖宫产率、副作用等指标。结果:观察组总产程时间为(9.3±3.7)h,对照组为(14.5±4.7)h,两组比较差异有统计学意义(P<0.01)。观察组剖宫产率为6%;对照组为60%,两组比较差异有统计学意义(P<0.01)。结论:欣普贝生促进宫颈成熟的效果明显优于催产素,并可缩短总产程,减少阴道出血量,降低剖宫产率。
OBJECTIVE: To observe the role of Hippophae in the promotion of cervical maturation in obstetrics. Methods: From October 2009 to September 2010, the gestation period in the obstetrics department of the Second Hospital of Jilin University was over 38 weeks. The Bishop cervical score was 6 points. There was no pregnancy complications, single head position, primipara requiring vaginal trial 100 cases were randomly divided into two groups: the observation group of 50 cases were given posterior fornix to promote cervical maturation, until the cervix open up to 3 cm, or appear too uterine contractions, fetal distress out; control group 50 cases of oxytocin to promote cervical maturation. Two groups of total labor, vaginal bleeding, neonatal asphyxia, cesarean section rate, side effects and other indicators. Results: The total duration of labor was (9.3 ± 3.7) h in the observation group and (14.5 ± 4.7) h in the control group, with significant difference between the two groups (P <0.01). The cesarean section rate was 6% in the observation group and 60% in the control group, with significant difference between the two groups (P <0.01). Conclusion: The effect of Enbutstemon to promote cervical ripening is obviously better than that of oxytocin, which can shorten the total labor process, reduce the amount of vaginal bleeding and reduce the rate of cesarean section.