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据报道口服避孕药对急性阑尾炎的生物特性有影响,为此本文研究了怀疑为急性阑尾炎而施行阑尾切除术的患者共253例,其中121例(占48%)为服用避孕药者。年龄为15～45岁,作者仔细询问了121例患者的月经周期及服避孕药情况。结果表明未服避孕药组急性阑尾炎的发生时间以黄体期为最高,比在月经周期的另一半时间高两倍多,而这种显著差别在服避孕药组却不出现。在服避孕药患者中发生坏疸性及穿孔的阑尾比未服药组显著增多,其中76%是发生于月经期及滤泡期。本研究提示,于月经周期的不同阶段,急性阑尾炎发生频率和手术中发现的阑尾炎症的程度,在服避孕药组和未服药组相差显著。
Oral contraceptives have been reported to affect the biological properties of acute appendicitis. To this end, 253 patients with suspected appendectomy undergoing appendectomy were investigated, of whom 121 (48%) were contraceptives. Aged 15 to 45 years old, the author carefully asked 121 cases of menstrual cycle and taking contraceptives. The results showed that the incidence of acute appendicitis before taking contraceptives group was highest in the luteal phase, more than twice than in the other half of the menstrual cycle, and this significant difference in the dose of contraceptives does not appear. In patients with contraceptives occurred in patients with jaundice and perforation of the appendix than the non-medication group was significantly increased, of which 76% occurred in the menstrual period and follicular phase. This study suggests that at different stages of the menstrual cycle, the frequency of acute appendicitis and the degree of appendicitis found during surgery are significantly different between the contraceptive and non-medication groups.