Menetrier病又名胃粘膜巨肥厚症或巨大肥厚性胃炎,迄今文献报告约有200例。近本院收治1例,报告如下。病例报告患者男性,46岁,木工,病案号46391,河北省人。主诉上腹不适,食后胀满疼痛,偶有黑便,下肢浮肿年余,近来消瘦。既往史无特殊。住院查体,TPR正常,除左上腹稍有触痛外,未发现异常。钡餐检查见胃呈“J”字形,胃体及部分胃窦可见多发息肉状指压充盈缺损,境界清晰,胃粘膜皱襞不整,有挤压集簇,且中断,但胃襞尚柔软, Menetrier disease, also known as gastric mucosal hypertrophy or hypertrophic gastritis, has reported about 200 cases so far. Nearly 1 case was admitted to our hospital. The report is as follows. Case Report Patient Male, 46 years old, woodworking, case number 46391, Hebei Province. He complained of discomfort on the upper abdomen, fullness of pain after eating, occasional black stools, swelling of the lower limbs for more than a year, and recent weight loss. No special past history. In the hospital examination, the TPR was normal. No abnormalities were found except for a slight tenderness in the left upper quadrant. The barium meal examination showed a “J” shape in the stomach, multiple polypoid shiatsu filling defects in the stomach and part of the gastric antrum, clear boundary, incomplete wrinkling of the gastric mucosa, squeezing and clustering, and interruption, but the gastric fistula was still soft.